Scientists have identified the location of the body that may be the epicenter of the first coliform disease caused by the Novel Corona virus.Scientists have discovered that the corona virus infects the body by targeting nasal cells.
This was revealed in a medical study conducted in the United States.
Research from the Johns Hopkins University School of Medicine on experiments on human cell samples revealed that the corona virus infects cells that support the sense of smell in the nose, which is located inside the upper part of the nose. They are also present in the lungs.
These helper cells are essential for the function and formation of olfactory cells.
The findings are part of a preliminary study of nasal cells that could help advance the search for the best target for drugs to treat COD 19, while also clarifying that the virus is endemic. Why do most people lose their sense of smell?
The research summary was published in a letter in the journal European Receptive Journal.
Researchers say that people who lose their sense of smell as a result of Code 19 often do not see other nasal problems, and our research will help determine why and how this happens, while possibly But you may also have the opportunity to discover the best treatment.
Scientists already know that the corona virus binds to different types of human cells with the help of a receptor called S2.
To learn more about this relationship, researchers closely examined the levels of S2 in nasal tissues.
These tissues were collected from 19 men and women and they found that the level of S2 in the nostril cells is very high.
These cells are located where the neurons that help smell are present, and the researchers said that this part of the nose may be particularly vulnerable to disease and possibly the only affected part, There may be no symptoms.
In view of this, researchers urged people to use face masks and wear them properly.
Research has shown that S2s are more common at this location than other parts of the nose, as large amounts of S2 are associated with the sense of smell, which is why some people with code 19 suffer from sniffing. Deprived of the sense of.
Earlier in April, a study found that two types of nasal cells, goblet and celiac, contain high levels of code 19 entry proteins, which allow the virus to enter other cells. ۔
The discovery was made by the Wellcome Sanger Institute in the UK, the University Medical Center in Groningen in the Netherlands, the University of Cte d’Azur in France, CNRS, NICE and others, which helps explain why the disease spreads so fast. Has been
The study found that cells in the eyes and a few other organs also become the center of the virus’s entry protein, while researchers explained how an entry protein can be regulated and possible treatment targets.
The new novice corona virus affects the lungs and respiratory tract, and patients show flu-like symptoms such as fever, cough, and sore throat, with many people showing no symptoms but still carrying the virus. Move.
The worst cases are pneumonia, which can lead to death.
The researchers said: “We discovered that the receptor protein S2 and TMPRSS2 activate the entry protein of SARS CoV2 and deliver it to cells in various organs, including cells inside the nose. ۔
Upon further analysis, the researchers found that the mucus-forming goblets and ciliated cells contained the highest amounts of the proteins of the Code 19 virus, which may have been the primary source of infection for the virus.
The researchers said that this is the first time that these specific nasal cells have been linked to code 19 and that several elements play a role in the transmission of the virus, but our findings show that the location of these cells is very fast. Helps to spread.
The virus’s two entries, S2 and TMPRSS2, were also detected in the cornea and intestinal cells, suggesting another possible route of the virus from the eye and tear ducts.
When cells are damaged by infection, a number of immune genes are activated, and this study found that the production of the S2 receptor in nasal cells changes when the immune genes are activated.
The researchers said that this information would help in understanding the spread of corona virus and it is important to know what kind of cells play a role in the transmission of the virus, which could lead to possible therapies. It will be possible to reduce the rate of spread.